Non-Random Association of the Polymorphic Taq I Restriction Site, Located 3 KB 5′ to the Human δ-Globin Gene, with the Polymorphic Hind III Sites within the Gγ- and Aγ-Globin Genes
نویسندگان
چکیده
منابع مشابه
Heterozygosis deficit of polymorphic markers linked to the β-globin gene cluster region in the Iranian population
Objective(s): Iran is considered as one of the high-prevalence areas for β-thalassemia with a rate of about 10% carrier frequency. Molecular diagnosis of the disease is performed both by direct sequencing and indirectly by the use of polymorphic markers present in the beta globin gene cluster. However, to date there is no reliable information on the application of the markers in the Iranian pop...
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Beta-Globin Gene Cluster Haplotypes in Iranian Sickle Cell Patients: Relation to Some Hematologic
Background: Sickle cell anemia is relatively common in Khuzestan province located in Southwest Iran. The characteristics of sickle cell disease in Iran are apparently different from other regions some of these characteristics might be related to β-chain haplotypes. The purpose of this study was to determine the frequency of β-chain haplotypes in 50 patients with homozygous sickle cell anemia in...
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ژورنال
عنوان ژورنال: Acta Haematologica
سال: 1984
ISSN: 0001-5792,1421-9662
DOI: 10.1159/000206393